## Purpose
The Healthcare Common Procedure Coding System (HCPCS) code A9528 is assigned to a specific medical product used in diagnostic imaging. It describes “Iodine I-125 sodium iodide, diagnostic, per millicurie.” This isotope is utilized in nuclear medicine, particularly for performing imaging studies or scans that require the use of a radioactive tracer to help visualize internal structures.
In particular, the imaging agent represented by HCPCS code A9528 is deployed in gamma cameras or other scintillation-based imaging systems. These systems detect the gamma rays emitted by the radioactive iodine, allowing for detailed and functional imaging of various organs, most commonly the thyroid gland, due to iodine’s affinity for this tissue. The purpose of the administration of A9528 is thus to aid in the functional analysis and localization of specific diseases, particularly those involving the thyroid or other Iodine-sensitive tissues.
## Clinical Indications
HCPCS code A9528 is mainly used in diagnostic imaging procedures for the thyroid. Iodine I-125, specifically coded here, is concentrated in the thyroid gland, where it assists in pinpointing abnormalities, including possible presence of carcinoma, hyperthyroidism, or goiters. It is particularly useful in identifying areas of abnormal iodine uptake, which can reveal nodules or other dysfunctions.
It can also be employed in the delineation of other tissues, primarily when further functional analysis is required to complement structural imaging. Providing vital information for endocrinologists and nuclear medicine specialists, the I-125 tracer offers valuable insights into the metabolic activity of the target tissue.