1F43: Malaria due to Plasmodium ovale

ICD-11 code 1F43 corresponds to cases of malaria caused by infection with Plasmodium ovale, a species of parasite that can be transmitted to humans through the bite of an infected mosquito. This type of malaria is characterized by symptoms such as fever, chills, sweats, headache, and body aches. In severe cases, Plasmodium ovale infection can lead to complications such as organ failure or death if not promptly treated with appropriate antimalarial medications.

Plasmodium ovale is one of several species of Plasmodium parasites that can cause malaria in humans, with others including Plasmodium falciparum, Plasmodium vivax, and Plasmodium malariae. While Plasmodium ovale infection is less common than infections with other species such as Plasmodium falciparum, it is important to accurately diagnose and treat cases of malaria due to Plasmodium ovale to prevent complications and reduce the risk of transmission to others. The use of ICD-11 code 1F43 helps healthcare providers and public health officials track and monitor cases of Plasmodium ovale malaria for surveillance and research purposes, contributing to efforts to control and eliminate malaria worldwide.

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#️⃣  Coding Considerations

In the world of medical coding, the SNOMED CT code equivalent to the ICD-11 code 1F43 (Malaria due to Plasmodium ovale) is 238831005. This SNOMED CT code specifically identifies cases of malaria caused by the Plasmodium ovale parasite, a less common type of malaria compared to Plasmodium falciparum or Plasmodium vivax. The use of standardized codes like SNOMED CT facilitates accurate and precise communication among healthcare professionals and organizations, ensuring that patient information is consistently interpreted and treated. By linking ICD-11 codes with SNOMED CT codes, healthcare systems can improve interoperability and data exchange, ultimately leading to better patient care and outcomes. The transition from ICD-11 codes to SNOMED CT codes signifies a shift towards more comprehensive and detailed medical documentation and terminology.

In the United States, ICD-11 is not yet in use. The U.S. is currently using ICD-10-CM (Clinical Modification), which has been adapted from the WHO’s ICD-10 to better suit the American healthcare system’s requirements for billing and clinical purposes. The Centers for Medicare and Medicaid Services (CMS) have not yet set a specific date for the transition to ICD-11.

The situation in Europe varies by country. Some European nations are considering the adoption of ICD-11 or are in various stages of planning and pilot studies. However, as with the U.S., full implementation may take several years due to similar requirements for system updates and training.

🔎  Symptoms

Malaria due to Plasmodium ovale, designated as 1F43, is characterized by a range of symptoms that typically manifest within a few weeks of being bitten by an infected mosquito. Initially, individuals may experience flu-like symptoms such as fever, chills, headaches, and joint pain. As the disease progresses, patients may also present with nausea, vomiting, and diarrhea, leading to dehydration and weakness.

In some cases, individuals with 1F43 may develop anemia due to the destruction of red blood cells by the malaria parasite. This can result in symptoms such as fatigue, pale skin, and shortness of breath. Furthermore, complications such as organ failure, seizures, and coma may occur in severe cases of Plasmodium ovale infection.

Another common symptom of 1F43 is the occurrence of cyclical fever episodes, characterized by fever spikes that occur at regular intervals. These fever patterns typically coincide with the release of merozoites from infected red blood cells, signaling the cyclical nature of the malaria infection. Additionally, individuals with 1F43 may also exhibit an enlarged spleen, a common characteristic of malarial infection caused by various Plasmodium species.

🩺  Diagnosis

Diagnosis methods for 1F43 (Malaria due to Plasmodium ovale) typically involve a combination of clinical evaluation, microscopy, rapid diagnostic tests (RDTs), and molecular assays. Clinicians may consider a patient’s symptoms, medical history, travel history, and exposure to mosquito bites when assessing the likelihood of malaria due to P. ovale.

Microscopy remains a key tool in the diagnosis of P. ovale malaria, as it allows for the identification of Plasmodium species in a blood smear. Thick and thin blood smears are stained and examined under a microscope to detect the presence of P. ovale parasites. Parasitemia levels can be quantified to assess the severity of the infection.

Rapid diagnostic tests (RDTs) are used to quickly detect specific antigens produced by P. ovale parasites in a patient’s blood. RDTs are simple to use and provide rapid results, making them valuable tools in settings where microscopy may not be readily available. However, false negatives can occur with RDTs, particularly when parasitemia levels are low.

Molecular assays, such as polymerase chain reaction (PCR) tests, can provide highly sensitive and specific detection of P. ovale parasites in a patient’s blood. PCR can differentiate between different Plasmodium species and detect low levels of parasitemia that may be missed by microscopy or RDTs. Molecular assays are particularly useful in confirming a diagnosis when microscopy results are inconclusive.

💊  Treatment & Recovery

Treatment for Malaria due to Plasmodium ovale typically involves the use of antimalarial medications. The specific medication and duration of treatment may vary depending on factors such as the severity of the infection and the patient’s age and overall health. Commonly prescribed medications for this type of malaria include chloroquine, primaquine, and mefloquine.

In cases of uncomplicated Plasmodium ovale malaria, chloroquine is often the first-line treatment. Primaquine may also be prescribed to help prevent relapse of the infection. Patients with severe malaria or those who are unable to tolerate oral medications may require hospitalization and intravenous (IV) medications, such as quinine or artesunate.

Recovery from Malaria due to Plasmodium ovale is typically successful with prompt and appropriate treatment. Most patients experience significant improvement within 48 to 72 hours of starting antimalarial medications. It is important for patients to complete the full course of treatment as prescribed by their healthcare provider to ensure complete eradication of the parasite and prevent recurrence of the infection. Follow-up appointments may be necessary to monitor the patient’s recovery and ensure that the infection has been fully cleared.

🌎  Prevalence & Risk

In the United States, Malaria due to Plasmodium ovale is considered rare. Cases are typically seen in individuals who have recently traveled to regions where this specific type of malaria is prevalent, such as sub-Saharan Africa. Due to effective surveillance and prevention measures, the local transmission of Malaria due to Plasmodium ovale in the United States is uncommon.

In Europe, the prevalence of Malaria due to Plasmodium ovale varies depending on the country. In regions where malaria is endemic, such as parts of southern Europe, cases of this specific type of malaria may be more common. However, overall, the incidence of Malaria due to Plasmodium ovale in Europe is relatively low compared to other types of malaria. Travelers returning from endemic areas are the main source of imported cases in Europe.

In Asia, Malaria due to Plasmodium ovale is more prevalent in certain countries with tropical climates, such as Indonesia and Papua New Guinea. These regions are known for having high rates of malaria transmission, including Plasmodium ovale. Local populations living in endemic areas are at greater risk of contracting this type of malaria. Travelers visiting these regions are advised to take precautions to prevent mosquito bites and seek medical attention if symptoms of malaria develop.

In Africa, Malaria due to Plasmodium ovale is endemic in many countries, particularly in sub-Saharan Africa. The prevalence of this specific type of malaria varies across different regions within Africa. Factors such as climate, mosquito vectors, and human behavior contribute to the spread of Malaria due to Plasmodium ovale. Efforts to control and eliminate malaria in Africa have made progress, but challenges remain in reducing the burden of this disease.

😷  Prevention

Prevention of 1F43 (Malaria due to Plasmodium ovale) primarily involves avoiding exposure to infected mosquitoes. This can be achieved by using insect repellent, wearing long sleeves and pants, and sleeping under mosquito nets. Additionally, individuals should take precautionary measures in endemic areas, such as staying indoors during dusk and dawn when mosquitoes are most active.

Travelers to regions where Plasmodium ovale is prevalent should consider taking antimalarial medication as a prophylactic measure. Consultation with a healthcare provider is essential to determine the most appropriate medication based on individual factors, such as medical history and potential drug interactions. It is important to adhere to the recommended dosage regimen and continue taking the medication for the prescribed duration, even after returning from the affected area.

Enhanced surveillance and control measures, such as vector control programs and early diagnosis and treatment of infected individuals, are vital in preventing the spread of 1F43. Public health authorities should prioritize these strategies to effectively reduce the incidence of Malaria due to Plasmodium ovale. Additionally, raising awareness among communities about the risks of malaria and promoting practices to prevent mosquito bites can contribute to the overall prevention efforts.

Malaria due to Plasmodium malariae (1F42) is caused by infection with the Plasmodium malariae parasite. This form of malaria is often milder than other types. Symptoms may include recurring fevers, chills, and headaches. Diagnosis is typically made through blood tests to detect the presence of the parasite.

Malaria due to Plasmodium vivax (1F44) is caused by infection with the Plasmodium vivax parasite. This form of malaria can cause recurring fevers and can lead to severe complications if left untreated. Diagnosis is typically made through blood tests to detect the presence of the parasite. Treatment usually involves a course of antimalarial medications.

Malaria due to Plasmodium falciparum (1F45) is caused by infection with the Plasmodium falciparum parasite. This form of malaria is the most severe and can be life-threatening if not treated promptly. Symptoms may include high fever, severe headaches, and organ failure. Diagnosis is typically made through blood tests to detect the presence of the parasite. Treatment requires prompt medical attention and a course of antimalarial medications.

Malaria due to mixed species (1F40) is a form of malaria caused by infection with multiple species of Plasmodium parasites. This can lead to more severe symptoms and complications than infections with a single parasite species. Diagnosis and treatment may be more complex due to the presence of multiple parasite species. Prompt medical attention is essential in cases of mixed species malaria to prevent serious illness and complications.

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