2E65.1: Lobular carcinoma in situ of breast, pleomorphic subtype

ICD-11 code 2E65.1 signifies lobular carcinoma in situ of the breast, specifically the pleomorphic subtype. Lobular carcinoma in situ is a non-invasive condition where abnormal cells are found in the lobules of the breast but have not spread to surrounding tissues. The pleomorphic subtype is characterized by cells that vary in size, shape, and staining properties under a microscope.

This code is used by healthcare professionals and medical coders to accurately document and track cases of lobular carcinoma in situ with the pleomorphic subtype. It helps in the classification of breast cancer subtypes for research, treatment, and statistical purposes. The designation of a specific subtype like pleomorphic aids in determining the appropriate course of treatment for patients with this particular form of the disease.

Understanding the nuances of different subtypes of lobular carcinoma in situ, such as pleomorphic, is crucial for accurate diagnosis and treatment planning. By using a detailed coding system like ICD-11, healthcare providers can ensure consistency and precision in identifying and managing different types of breast cancer. Overall, the use of specific codes like 2E65.1 helps in improving communication, research, and outcomes in the field of oncology.

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#️⃣  Coding Considerations

The SNOMED CT code equivalent to ICD-11 code 2E65.1 is 69022008. This code specifically represents the diagnosis of lobular carcinoma in situ of the breast, pleomorphic subtype, in the SNOMED CT terminology. The SNOMED CT coding system is utilized by healthcare professionals to accurately classify and document medical conditions, procedures, and diagnoses in electronic health records. With its extensive hierarchy system and comprehensive terminology, SNOMED CT allows for precise and detailed documentation of patient conditions. By using the SNOMED CT code 69022008 for lobular carcinoma in situ of the breast, pleomorphic subtype, healthcare providers can ensure consistency and interoperability in medical data exchange across different healthcare settings. It is essential for healthcare professionals to understand the importance of proper coding and terminology standards in order to improve patient care outcomes and facilitate effective communication among healthcare providers.

In the United States, ICD-11 is not yet in use. The U.S. is currently using ICD-10-CM (Clinical Modification), which has been adapted from the WHO’s ICD-10 to better suit the American healthcare system’s requirements for billing and clinical purposes. The Centers for Medicare and Medicaid Services (CMS) have not yet set a specific date for the transition to ICD-11.

The situation in Europe varies by country. Some European nations are considering the adoption of ICD-11 or are in various stages of planning and pilot studies. However, as with the U.S., full implementation may take several years due to similar requirements for system updates and training.

🔎  Symptoms

Symptoms of 2E65.1 (Lobular carcinoma in situ of breast, pleomorphic subtype) may include a palpable mass or thickening in the breast tissue. Patients may also experience changes in the appearance or texture of the skin over the affected area, such as redness or dimpling.

Additionally, individuals with this subtype of lobular carcinoma in situ may notice nipple discharge that is bloody or clear. Other symptoms can include breast pain or tenderness, as well as changes in the size or shape of the breast. It is important for individuals experiencing these symptoms to consult with a healthcare provider for further evaluation and testing.

In some cases, patients with 2E65.1 (Lobular carcinoma in situ of breast, pleomorphic subtype) may not experience any noticeable symptoms. This highlights the importance of regular breast cancer screenings, such as mammograms, to detect abnormalities early on. Early detection and treatment can lead to better outcomes and prognosis for individuals with this condition.

🩺  Diagnosis

The diagnosis of Lobular carcinoma in situ of breast, pleomorphic subtype (2E65.1) often involves a combination of imaging techniques and biopsy. Mammograms are typically the initial screening tool used to detect abnormal breast growths, followed by further imaging studies such as ultrasound or MRI for additional evaluation. If suspicious findings are identified, a biopsy is performed to confirm the presence of cancer cells.

During a biopsy, a sample of tissue is collected from the breast and examined under a microscope to determine the presence of cancerous cells. In the case of Lobular carcinoma in situ of breast, pleomorphic subtype, pathologists will be looking for characteristic pleomorphic features indicative of this specific subtype. Special staining techniques may be used to distinguish this subtype from other forms of breast cancer.

In addition to imaging studies and biopsy, genetic testing may also be recommended for patients diagnosed with Lobular carcinoma in situ of breast, pleomorphic subtype. Certain genetic mutations, such as alterations in the CDH1 gene, have been associated with an increased risk of developing lobular carcinoma in situ. Testing for these mutations may help guide treatment decisions and inform the patient’s overall management plan.

💊  Treatment & Recovery

Treatment for Lobular carcinoma in situ of the breast, pleomorphic subtype (2E65.1) often involves a combination of surgical intervention, such as lumpectomy or mastectomy, and adjuvant therapies such as radiation therapy or hormone therapy. The goal of treatment is to remove the abnormal cells and prevent the development of invasive breast cancer. Patients may also undergo genetic testing to identify any underlying mutations that could increase their risk for recurrence.

Surgical options for Lobular carcinoma in situ of the breast, pleomorphic subtype may include a lumpectomy, which involves removing the affected breast tissue, or a mastectomy, which involves removing the entire breast. The choice of surgery will depend on the size and location of the abnormal cells, as well as the patient’s preferences and overall health. In some cases, surgeons may also perform a sentinel lymph node biopsy to determine if the cancer has spread to nearby lymph nodes.

In addition to surgery, patients with Lobular carcinoma in situ of the breast, pleomorphic subtype may also undergo adjuvant therapies such as radiation therapy or hormone therapy. Radiation therapy uses high-energy beams to target and destroy any remaining cancer cells, while hormone therapy works by blocking the hormones that can fuel the growth of certain types of breast cancer. These treatments are often used in combination to help reduce the risk of recurrence and improve outcomes for patients with this subtype of breast cancer.

🌎  Prevalence & Risk

In the United States, 2E65.1 (Lobular carcinoma in situ of breast, pleomorphic subtype) has a relatively low prevalence compared to other subtypes of breast cancer. This subtype accounts for approximately 5-10% of all cases of lobular carcinoma in situ. However, the exact prevalence of this subtype in the United States is not well documented due to the rarity of the pleomorphic subtype.

In Europe, the prevalence of 2E65.1 is slightly higher than in the United States. This subtype of lobular carcinoma in situ is estimated to account for around 15% of all cases of lobular carcinoma in situ in Europe. The higher prevalence in Europe may be attributed to differences in genetic and environmental factors that influence the development of breast cancer.

In Asia, the prevalence of 2E65.1 is similar to that in the United States, with this subtype accounting for approximately 5-10% of all cases of lobular carcinoma in situ. However, there may be regional variations in prevalence within Asia due to differences in lifestyle factors, genetic predisposition, and access to healthcare.

In Australia, the prevalence of 2E65.1 is comparable to that in Europe and the United States, with this subtype accounting for around 15% of all cases of lobular carcinoma in situ. As in other regions, the true prevalence of the pleomorphic subtype may be underestimated due to challenges in accurately diagnosing and classifying this rare form of breast cancer.

😷  Prevention

One way to prevent Lobular Carcinoma In Situ (LCIS) of the breast is through regular breast cancer screening. Mammograms and clinical breast exams can help detect the condition early, allowing for timely intervention. By catching LCIS at an early stage, it may be possible to prevent its progression to invasive breast cancer.

Maintaining a healthy lifestyle can also help reduce the risk of developing LCIS. This includes maintaining a healthy weight, engaging in regular physical activity, and avoiding excessive alcohol consumption. A diet high in fruits, vegetables, and whole grains can also lower the risk of breast cancer, including LCIS.

For individuals with a family history of breast cancer, genetic counseling and testing may be beneficial. Identifying genetic mutations such as BRCA1 and BRCA2 can help individuals understand their risk for developing breast cancer. With this knowledge, healthcare providers can develop personalized screening and prevention strategies to reduce the risk of developing LCIS.

Disease 2E65.0 (Lobular carcinoma in situ of breast, non-pleomorphic subtype) is a similar condition to Lobular carcinoma in situ of breast, pleomorphic subtype. While both are non-invasive forms of breast cancer, they differ in terms of their cellular characteristics. The non-pleomorphic subtype typically presents as uniform, small cells within the lobules of the breast, whereas the pleomorphic subtype exhibits more variable and irregular cell shapes.

Disease 2E66.0 (Ductal carcinoma in situ of breast) shares similarities with Lobular carcinoma in situ of breast, pleomorphic subtype in that they are both non-invasive forms of breast cancer. However, ductal carcinoma in situ arises from the milk ducts of the breast, while lobular carcinoma in situ originates from the lobules. Additionally, ductal carcinoma in situ may vary in appearance and behavior compared to lobular carcinoma in situ, depending on the specific subtype.

Disease 2C50.9 (Carcinoma in situ of other and unspecified parts of the head, face, and neck) is another condition that bears some resemblance to Lobular carcinoma in situ of breast, pleomorphic subtype. Both diseases are characterized by the presence of cancerous cells that have not invaded surrounding tissues. However, they differ in terms of their anatomical location and specific cell characteristics. Carcinoma in situ of the head, face, and neck can manifest in various structures within this region, while Lobular carcinoma in situ is specific to the lobules of the breast.

In summary, Lobular carcinoma in situ of breast, pleomorphic subtype shares similarities with other non-invasive forms of cancer such as lobular carcinoma in situ of breast, non-pleomorphic subtype, ductal carcinoma in situ of breast, and carcinoma in situ of other and unspecified parts of the head, face, and neck. While these diseases may differ in their cellular characteristics and anatomical locations, they all represent early stages of cancer development that have not yet spread to surrounding tissues.

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